News archive

  • 2020

    Comprehensive mathematical model of the alternative complement pathway describing in vitro experimental- and clinical-data
    05. October, 2020

    We recently published a comprehensive mathematical model of the alternative complement pathway in the PLOS Computational Biology journal. Building on previous modelling efforts, in this work...

    Population PK/PD Modeling of Glenzocimab (ACT017) a Glycoprotein VI Inhibitor of Collagen‐Induced Platelet Aggregation
    05. June, 2020

    Glenzocimab (ACT017) is a humanized monoclonal antigen‐binding fragment (Fab) directed against the human platelet glycoprotein VI, a key receptor for collagen and fibrin that plays a major...

    Pharmacokinetics-pharmacodynamics of enmetazobactam combined with cefepime in a neutropenic murine thigh infection model
    17. April, 2020

    Third-generation cephalosporin (3GC)-resistant Enterobacteriaceae are classified as critical priority pathogens, with extended-spectrum β-lactamases (ESBLs) as principal resistance...