We had the opportunity to contribute to the Master’s program in pharmacokinetic modeling at Université Paris Cité.
Matthias Machacek presented a lecture on PK/PD modeling of small interfering RNA (siRNA) and antisense oligonucleotides (ASOs), and Elena Garcia Montoya presented on PK/PD modeling of antibody-drug conjugates (ADCs) and their clinical development.
The sessions covered key questions addressed by modeling, appropriate strategies across modalities, study design considerations, and how modeling supports decision-making throughout development.
Many thanks to the students and to Xavier Decleves, Professor and Director of the teaching unit 'Pharmacokinetics and Radiopharmacy', and Alicja Puszkiel, Associate Professor, for inviting us and trusting us with these lectures.